Hair Health & Treatments
✓ Medically Reviewed by Dr. William Rassman, MD
Platelet-Rich Plasma (PRP) & Exosome Therapy in Androgenetic Alopecia
Evaluating growth factor concentrations, centrifugation speeds, and micro-needling depth for non-surgical hair follicular stimulation.
Dr. William Rassman, MD • Diplomate, American Board of Hair Restoration Surgery
September 26, 2026 • 6 min read
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Mechanism of Growth Factor Action in the Hair Follicle
Platelet-Rich Plasma (PRP) delivers high concentrations of autologous growth factors—including PDGF, VEGF, EGF, and FGF-2—directly to dormant hair dermal papilla cells. This bio-stimulation reactivates micro-capillary networks around the follicle base.
PRP vs. Exosome Bio-Therapies
While PRP relies on autologous blood processing, extracellular vesicles (exosomes) derived from stem cells transport microRNAs and signalling proteins without requiring blood draws.
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Clinical Discussion & Reader Comments (1)
Michael R., RN
Sep 26, 2026
Excellent clinical summary. The point regarding donor harvest threshold is crucial for patient safety.
Clinical Contents