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Hair Health & Treatments ✓ Medically Reviewed by Dr. William Rassman, MD

Platelet-Rich Plasma (PRP) & Exosome Therapy in Androgenetic Alopecia

Evaluating growth factor concentrations, centrifugation speeds, and micro-needling depth for non-surgical hair follicular stimulation.

Dr. William Rassman, MD • Diplomate, American Board of Hair Restoration Surgery
September 26, 2026 • 6 min read
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Platelet-Rich Plasma (PRP) & Exosome Therapy in Androgenetic Alopecia

Mechanism of Growth Factor Action in the Hair Follicle

Platelet-Rich Plasma (PRP) delivers high concentrations of autologous growth factors—including PDGF, VEGF, EGF, and FGF-2—directly to dormant hair dermal papilla cells. This bio-stimulation reactivates micro-capillary networks around the follicle base.

PRP vs. Exosome Bio-Therapies

While PRP relies on autologous blood processing, extracellular vesicles (exosomes) derived from stem cells transport microRNAs and signalling proteins without requiring blood draws.

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MEDICAL PEER-REVIEW DISCLOSURE: The information presented in this guide is intended strictly for educational purposes and does not replace formal medical diagnosis or clinical treatment advice.

Clinical Discussion & Reader Comments (1)

Michael R., RN Sep 26, 2026

Excellent clinical summary. The point regarding donor harvest threshold is crucial for patient safety.

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